What is AOD-9604?

Overview

AOD-9604 is the C-terminal fragment of human growth hormone — engineered to retain the lipolytic (fat-burning) activity of GH while stripping out the growth and insulin-resistance effects. Metribolone-era research teams isolated this fragment to study whether GH’s fat-metabolism actions could be separated from its mitogenic ones. Why it keeps showing up in obesity-research literature: AOD-9604 stimulates lipolysis and inhibits lipogenesis in adipose tissue via a non-GHR mechanism, without the IGF-1 spike that drives water retention and joint pain on full-length GH. IF you need GH-like lipolytic activity without the growth-signaling payload, THEN AOD-9604 is the fragment with 20+ years of published pharmacology. SO it fits in protocols studying adipose mobilization, cartilage repair, or appetite-metabolism crossover. Independently verified at ≥99% purity.

Research areas

• Lipolysis pathway

  <p>Increases cAMP in adipocytes via a β3-adrenergic-like mechanism, stimulating hormone-sensitive lipase and driving triglyceride hydrolysis without activating the GH receptor.</p>

• Cartilage & joint research

  <p>In-vivo models of osteoarthritis show chondrogenic activity and reduced joint degeneration with AOD-9604 + hyaluronic acid co-administration.</p>

• Metabolic selectivity

  <p>Unlike full-length GH, AOD-9604 does not raise IGF-1 or induce insulin resistance in published human trials, making it useful for GH-effect-isolation studies.</p>

• Administration

  <p>Subcutaneous delivery is the most common route in published research. Reconstitute with bacteriostatic water; use reconstituted solution within 30 days at 2–8°C.</p>

Storage & handling

Lyophilized AOD-9604is stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

Frequently asked questions

What is AOD-9604?

AOD-9604 (AOD-9604) is a research compound studied in the area of metabolic. A modified fragment of hGH (amino acids 176–191). Studied for lipolytic and cartilage-repair endpoints without the growth-promoting side effects of full-length GH.

What is the CAS number of AOD-9604?

The CAS registry number of AOD-9604 is 221231-10-3.

How should AOD-9604 be stored?

Lyophilized AOD-9604 should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

How is the purity of AOD-9604 verified?

Every Woosh Labs batch of AOD-9604 is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.

Is AOD-9604 for human use?

No. AOD-9604 sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.