Research Library · Healing & regeneration
What is BPC-157?
BPC-157 (BPC-157) is a research compound studied in healing & regeneration. Pentadecapeptide fragment of gastric BPC. Studied for tendon repair, gut-barrier integrity, and localized angiogenesis.
Overview
BPC-157 is the fragment of gastric body-protection compound that keeps showing up in healing literature — tendon studies, gut-barrier models, angiogenesis assays, CNS protection models. A 15-amino-acid sequence that appears stable across oral, intraperitoneal, and intramuscular delivery in the published literature. Why researchers keep coming back to it: it triggers angiogenesis locally, upregulates growth-hormone receptors in damaged tendon, and stabilizes tight-junction integrity in gut epithelium — three mechanisms that together map to the slow-healing injuries most therapeutic agents ignore. IF recovery speed is the bottleneck in your protocol, THEN BPC-157’s combination of localized angiogenesis and anti-inflammatory signaling is why it’s the most-studied peptide in its class. SO it belongs in any study where the question is how fast can this heal, with what histology. Every batch ships with a CoA, verified at ≥99% purity.
Research areas
Tendon & muscle repair
<p>Rat Achilles transection models show measurably faster tendon-to-bone healing and improved collagen organization when BPC-157 is administered post-injury. Multiple studies also report accelerated gastrocnemius and rotator-cuff repair at 10–50 μg/kg dosing ranges in rodents.</p>
Gut barrier integrity
<p>BPC-157 upregulates VEGF-mediated angiogenesis in damaged mucosa and restores tight-junction proteins (ZO-1, occludin) in models of colitis, IBD, and NSAID-induced ulceration. Commonly studied for its effect on the gut–brain axis.</p>
Angiogenesis & wound healing
<p>Upregulates growth-hormone receptor expression in fibroblasts and promotes local capillary formation. Referenced in cutaneous wound, burn, and anastomotic-healing literature.</p>
Neurological & systemic effects
<p>Published models in TBI, hepatic injury, and encephalopathy suggest neuroprotective and hepatoprotective signaling. Typically delivered intraperitoneally in rodents; sequence appears stable under gastric conditions.</p>
Published research
- Achilles detachment in rat and stable gastric…
PMID 16583442 — PubMed
- Effects of BPC-157 and TB-500 on Achilles tendon healing…
PMID 42542926 — PubMed
- Emerging Use of BPC-157 in Orthopaedic Sports Medicine
PMID 40756949 — PubMed
- Gastric pentadecapeptide body protection compound BPC…
PMID 30915550 — PubMed
- Gastric pentadecapeptide BPC 157 as an effective therapy…
PMID 18668315 — PubMed
- Injectable Peptide Therapy: A Primer for Orthopaedic and…
PMID 41476424 — PubMed
- Pentadecapeptide BPC 157 and the central nervous system
Sikiric P. et al., Neural Regen Res — 2022
- BPC 157 and standard angiogenic growth factors
Hsieh M. et al., Cardiovasc Res — 2017
Storage & handling
Lyophilized BPC-157is stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.
Frequently asked questions
- What is BPC-157?
- BPC-157 (BPC-157) is a research compound studied in the area of healing & regeneration. Pentadecapeptide fragment of gastric BPC. Studied for tendon repair, gut-barrier integrity, and localized angiogenesis.
- What is the CAS number of BPC-157?
- The CAS registry number of BPC-157 is 137525-51-0.
- How should BPC-157 be stored?
- Lyophilized BPC-157 should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.
- How is the purity of BPC-157 verified?
- Every Woosh Labs batch of BPC-157 is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.
- Is BPC-157 for human use?
- No. BPC-157 sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.
This page is for informational purposes for qualified researchers. All Woosh Labs products are for laboratory research use only and are not intended for human or veterinary use. Nothing here is medical advice or a claim of therapeutic effect.
