Research Library · Cognitive
What is DSIP?
DSIP (DSIP) is a research compound studied in cognitive. Delta Sleep-Inducing Peptide — a 9-amino-acid neuropeptide associated with slow-wave sleep and HPA-axis modulation.
Overview
DSIP was first isolated in the 1970s from cerebral venous blood of rabbits put into electrically-induced sleep. The sequence — Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu — turned out to be the same across every mammal tested. Evolutionarily conserved sequences that old tend to matter. What the sleep-research literature associates with it: increased delta-wave activity, reduced sleep-onset latency, and normalized HPA-axis cortisol rhythm. Beyond sleep, DSIP shows up in chronic-pain, alcohol-withdrawal, and stress-adaptation literature. IF the research question involves slow-wave sleep architecture or HPA-axis dysregulation, THEN DSIP is the peptide with the longest direct sleep-physiology record. SO it belongs in any protocol studying sleep quality, circadian reset, or stress-axis normalization. Verified purity ≥99%, CoA per batch.
Research areas
Sleep architecture
<p>EEG studies in rodents and humans report increased delta-wave (slow-wave) activity and improved sleep continuity after DSIP administration, particularly in subjects with disrupted baseline sleep.</p>
HPA axis regulation
<p>Normalizes cortisol rhythm in stress-disrupted models. Published in chronic-stress and adrenal-fatigue research contexts.</p>
Analgesic & anti-stress
<p>Documented analgesic effects in chronic-pain models and reduced stress-marker elevation under cold-water-swim and restraint-stress protocols.</p>
Stability
<p>DSIP is blood-brain-barrier permeable. Short plasma half-life (~7 minutes) is offset by downstream-receptor signaling duration. Lyophilized powder is stable when kept at 2–8°C.</p>
Storage & handling
Lyophilized DSIPis stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.
Frequently asked questions
- What is DSIP?
- DSIP (DSIP) is a research compound studied in the area of cognitive. Delta Sleep-Inducing Peptide — a 9-amino-acid neuropeptide associated with slow-wave sleep and HPA-axis modulation.
- What is the CAS number of DSIP?
- The CAS registry number of DSIP is 62568-57-4.
- How should DSIP be stored?
- Lyophilized DSIP should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.
- How is the purity of DSIP verified?
- Every Woosh Labs batch of DSIP is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.
- Is DSIP for human use?
- No. DSIP sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.
This page is for informational purposes for qualified researchers. All Woosh Labs products are for laboratory research use only and are not intended for human or veterinary use. Nothing here is medical advice or a claim of therapeutic effect.
