What is GHK-Cu?

Overview

GHK-Cu is glycyl-L-histidyl-L-lysine bound to copper(II) — a tripeptide your plasma produces naturally, until it doesn’t. Plasma levels fall from ~200 ng/mL in your 20s to ~80 ng/mL by your 60s. The literature tracks that decline against skin-repair capacity, hair-follicle regeneration, and wound-closure time. The mechanism that keeps it in the dermatology literature: GHK-Cu upregulates over 4,000 human genes, predominantly resetting them toward healthier, younger expression patterns. It stimulates collagen and elastin synthesis, modulates matrix-metalloproteinase activity, and delivers copper intracellularly in a non-toxic form. IF the research endpoint involves tissue remodeling — wound, hair, or skin — THEN GHK-Cu is the peptide with the densest published evidence. SO it belongs in any dermatology or regenerative-research protocol where the question is how well and how quickly tissue reorganizes. Batch-verified ≥99% purity. CoA included.

Research areas

• Collagen & elastin synthesis

  <p>In-vitro fibroblast studies show elevated type I collagen and elastin production in response to GHK-Cu at nanomolar concentrations. Effect is dependent on the copper-bound form — free GHK alone doesn&#8217;t replicate it.</p>

• Wound healing

  <p>Accelerated wound-closure rates and improved granulation-tissue quality in rodent and pig skin models. Frequently studied in diabetic-ulcer contexts.</p>

• Hair follicle research

  <p>Published in-vivo models demonstrate increased follicle size and anagen-phase prolongation. Topical delivery is the most common administration route in this research.</p>

• Antioxidant & anti-inflammatory

  <p>GHK-Cu acts as a copper chaperone, modulating reactive-oxygen-species generation and downregulating NF-κB-driven inflammatory transcription.</p>

Storage & handling

Lyophilized GHK-Cuis stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

Frequently asked questions

What is GHK-Cu?

GHK-Cu (GHK-Cu) is a research compound studied in the area of anti-aging. Copper-bound tripeptide that declines with age. Researched for collagen synthesis, wound closure, and skin remodeling.

What is the CAS number of GHK-Cu?

The CAS registry number of GHK-Cu is 49557-75-7.

How should GHK-Cu be stored?

Lyophilized GHK-Cu should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

How is the purity of GHK-Cu verified?

Every Woosh Labs batch of GHK-Cu is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.

Is GHK-Cu for human use?

No. GHK-Cu sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.