What is Glutathione?

Overview

Glutathione is a tripeptide — glutamate, cysteine, glycine — produced in the liver in quantities measured in grams per day. Every cell uses it. Every oxidative insult consumes it. Chronic inflammation, alcohol load, environmental toxin exposure, and aging all draw it down faster than the liver synthesizes it. Why it’s the most-studied antioxidant despite being the least marketed: GSH isn’t a scavenger like vitamin C — it’s the enzymatic substrate that glutathione peroxidase uses to neutralize peroxides. It recycles vitamin C and vitamin E back to active forms. It conjugates Phase-II liver detox metabolites. It’s the actual workhorse behind the antioxidant claims everyone else makes. IF the research endpoint involves oxidative stress — liver, neurological, skin, or systemic — THEN GSH depletion is almost certainly upstream of the damage marker being measured. SO restoring it is the intervention with the most consistent downstream effects across diverse models. Lyophilized reduced form, ≥99% purity. CoA included.

Research areas

• Oxidative stress defense

  <p>Primary substrate for glutathione peroxidase in neutralizing hydrogen peroxide and lipid peroxides. Reduces downstream damage markers (MDA, 8-OHdG) across virtually every oxidative-stress model in the literature.</p>

• Liver detoxification

  <p>Conjugates with Phase-II metabolites via glutathione-S-transferase enzymes. Essential for acetaminophen, benzene, and heavy-metal clearance. Depleted glutathione = depleted Phase-II capacity.</p>

• Immune & inflammation

  <p>Lymphocytes require intracellular GSH for proliferation and function. Low GSH correlates with TH2-shifted immune response and elevated NF-κB activity.</p>

• Stability & delivery

  <p>Reduced (GSH) form oxidizes rapidly in solution — use within 24 hours of reconstitution. Intravenous and nebulized delivery are the most commonly studied routes. Oral bioavailability is low due to gut GGT activity.</p>

Storage & handling

Lyophilized Glutathioneis stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

Frequently asked questions

What is Glutathione?

Glutathione (Glutathione) is a research compound studied in the area of cellular health. The master intracellular antioxidant. The molecule cells actually use to neutralize oxidative damage — first to deplete under stress.

What is the CAS number of Glutathione?

The CAS registry number of Glutathione is 70-18-8.

How should Glutathione be stored?

Lyophilized Glutathione should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

How is the purity of Glutathione verified?

Every Woosh Labs batch of Glutathione is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.

Is Glutathione for human use?

No. Glutathione sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.