What is Ipamorelin?

Overview

Ipamorelin is the most selective growth-hormone-releasing peptide developed. Unlike earlier GHRPs (GHRP-2, GHRP-6), it activates the ghrelin receptor (GHS-R1a) to trigger GH release without the off-target cortisol, prolactin, or aldosterone spike that complicates the interpretation of GHRP data. Why selectivity matters in research: A peptide that elevates cortisol + GH simultaneously is useless for studying GH-specific effects because you can’t isolate the variable. Ipamorelin’s clean profile lets researchers attribute downstream changes to GH release alone. IF the research question is endogenous GH pulsatility with minimal confounders, THEN Ipamorelin is the GHRP with the most defensible selectivity profile. SO it’s the default choice when pairing a GHRP with a GHRH analog (CJC-1295) in GH-axis research. Batch-verified ≥99% purity.

Research areas

• Receptor selectivity

  <p>Selective GHS-R1a agonist. Unlike GHRP-2/6, it does not stimulate the HPA axis or lactotrophs — no cortisol, prolactin, or ACTH elevation in published human trials.</p>

• Pairing with GHRH

  <p>Standard research pairing is Ipamorelin + CJC-1295: parallel activation of two independent pituitary pathways produces additive GH release.</p>

• GH pulse fidelity

  <p>Preserves natural diurnal GH rhythm — important because tonic GH exposure desensitizes the GH receptor while pulsatile exposure does not.</p>

• Administration

  <p>Subcutaneous injection, typically 200–300 μg per dose in rodent research. Use reconstituted solution within 30 days at 2–8°C.</p>

Published research

• Ghrelin is a growth-hormone-releasing acylated peptide from stomach

  PMID 10604470 — PubMed

• GHRP-6 is able to stimulate cortisol and ACTH release in patients…

  PMID 12809173 — PubMed

• Growth hormone-releasing effect of oral growth hormone…

  PMID 7581965 — PubMed

• Growth hormone-releasing peptides

  PMID 9186261 — PubMed

• I and IGF binding protein concentrations to growth hormone (GH…

  PMID 19351723 — PubMed

• induced ACTH release in patients with addison's disease: effect of…

  PMID 12739742 — PubMed

Storage & handling

Lyophilized Ipamorelinis stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

Frequently asked questions

What is Ipamorelin?

Ipamorelin (Ipamorelin) is a research compound studied in the area of longevity & anti-aging. A selective GHRP. Triggers GH release without elevating cortisol, prolactin, or aldosterone — the cleanest ghrelin-mimetic pharmacology available.

What is the CAS number of Ipamorelin?

The CAS registry number of Ipamorelin is 170851-70-4.

How should Ipamorelin be stored?

Lyophilized Ipamorelin should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

How is the purity of Ipamorelin verified?

Every Woosh Labs batch of Ipamorelin is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.

Is Ipamorelin for human use?

No. Ipamorelin sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.