What is Selank?

Overview

Selank is a heptapeptide derived from tuftsin — a tetrapeptide your spleen produces as part of immune signaling. The Russian pharmacology group that developed it was looking for an anxiolytic that didn’t produce sedation, dependence, or cognitive blunting. They got one. What the behavioral-pharmacology literature converges on: Selank modulates GABAergic tone without binding the benzodiazepine site, upregulates BDNF expression, and alters enkephalin breakdown — three mechanisms that map to reduced anxiety, maintained alertness, and improved memory consolidation in rodent models. IF the research question is anxiolytic effect without the cognitive cost, THEN Selank is the peptide with the longest clinical track record outside Western pharmacopoeias. SO it belongs in any protocol studying stress response, learning under load, or GABAergic tone without benzodiazepine side-effects. Independently verified. CoA in every order.

Research areas

• Anxiolytic mechanism

  <p>Modulates GABAergic tone indirectly and alters enkephalin degradation by inhibiting enkephalinase. Rodent elevated-plus-maze and open-field studies show anxiolytic effect without sedation across a 100–500 μg/kg range.</p>

• Memory & cognition

  <p>Upregulates BDNF in hippocampal tissue and improves performance on passive-avoidance and water-maze tasks. Commonly studied under stress-impaired learning conditions.</p>

• Immune modulation

  <p>Derived from tuftsin, Selank retains immunomodulatory properties — upregulates IL-6 and IFN-γ in challenged tissue, used in Russian clinical literature alongside anxiety research.</p>

• Administration

  <p>Intranasal administration is the most frequently studied route; bioavailability is acceptable across nasal mucosa. Subcutaneous delivery is also used in rodent work.</p>

Storage & handling

Lyophilized Selankis stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

Frequently asked questions

What is Selank?

Selank (SELANK) is a research compound studied in the area of cognitive. Synthetic tuftsin analog studied as a non-benzodiazepine anxiolytic. Calm without sedation, focus without stimulation.

What is the CAS number of Selank?

The CAS registry number of Selank is 129954-34-3.

How should Selank be stored?

Lyophilized Selank should be stored at –20 °C protected from light. Once reconstituted with bacteriostatic water, store at 2–8 °C and use within 30 days for maximum stability.

How is the purity of Selank verified?

Every Woosh Labs batch of Selank is independently tested by third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis published verifying ≥99% purity.

Is Selank for human use?

No. Selank sold by Woosh Labs is strictly for in-vitro laboratory research by qualified professionals. It is not for human or veterinary use of any kind.