Snap-8

10 × 10mg

An octapeptide SNARE-complex inhibitor — topical research alternative to botulinum toxin for expression-line research.

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About Snap-8

SNAP-8 is a topically-delivered octapeptide that inhibits the SNARE complex — the same molecular machinery that botulinum toxin paralyzes via proteolysis. Instead of cleaving SNARE proteins (the irreversible BOTOX mechanism), SNAP-8 competes with the 25-kDa SNAP-25 subunit for docking, reducing neurotransmitter vesicle fusion. Why the competitive mechanism is interesting in research: BOTOX’s effect is weeks-long because proteolytic cleavage is irreversible. SNAP-8’s competitive binding is reversible and localized — it lets researchers study SNARE-complex dynamics without permanent neuromuscular disruption. IF the research endpoint is reversible SNARE-complex inhibition or expression-line pharmacology, THEN SNAP-8 is the tool peptide with the topical-research track record. SO it fits in dermal-research protocols investigating fine-line biomarkers or neurotransmission-dependent tissue signals. ≥99% HPLC verified.

Specifications

CAS number: 868844-74-0
Molecular formula: C42H72N16O15S
Molecular weight: 1073.20 g/mol
Purity: >99% HPLC
Form: Lyophilized powder
Storage: Store at 2–8°C

For laboratory research use only. Not for human or veterinary use.